Researchers at the National Institutes of Health Clinical Center, in collaboration with extramural organizations, have sequenced nearly the entire genome of human, mouse and rat Pneumocystis. This organism causes a life-threatening pneumonia in immunosuppressed hosts. Pneumocystis was one of the first infections that led to the initial recognition of the HIV/AIDS epidemic. It has been responsible for thousands of deaths over the past 30 years and remains a significant risk in the HIV/AIDS population as well as in transplant recipients and other immunosuppressed patients. Findings were published in Nature Communications. NIH scientists collaborated with investigators from the Broad Institute and Leidos, Inc.
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